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An estrogen-dependent condition can be that relating to the differentiation in the steroid sex hormone that is associated with the female reproductive system and sex characteristics. [1] These conditions can fall under the umbrella of hypoestrogenism, hyperestrogenim, or any sensitivity to the presence of estrogen in the body.
Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
It can manifest as precocious puberty, and is caused by abnormally high levels of testosterone or estrogen, crucial hormones for sexual development. In some cases, it may be caused by a tumor, which can be malignant, but is more commonly benign. [2] Anabolic steroids may also be a major cause of high androgen and estrogen functional activity.
Starting puberty significantly early — younger than age 8 in girls, 9 in boys — may have health effects lasting into adulthood, including higher risks of breast cancer, diabetes and heart disease.
Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
Hormone replacement therapy consisting of systemic treatment with estrogen alone or in combination with a progestogen, has well-documented and considerable beneficial effects on the skin of postmenopausal women. [25] [26] These benefits include increased skin collagen content, skin thickness and elasticity, and skin hydration and surface lipids.
Side effects of EEs include nausea, breast tension, edema, and breakthrough bleeding among others. [8] It is an estrogen, or an agonist of the estrogen receptors, the biological target of estrogens like estradiol. [5] [3] [4] EEs are a prodrug mainly of estradiol and to a lesser extent of equilin. [5] EEs were introduced for medical use by 1970 ...
Since several health issues can cause low estrogen, no one-size-fits-all medication can treat low estrogen-related hair loss. Your healthcare provider may suggest using medication to boost your ...