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It is also approved for treatment of major depressive disorder in adolescents and children 8 years of age and over. [11] It has also been used to treat premature ejaculation. [2] Fluoxetine is taken by mouth. [2] Common side effects include loss of appetite, nausea, diarrhea, headache, trouble sleeping, dry mouth, and sexual
Because of their side effects and interaction risk, most MAOIs have been replaced by newer antidepressants over the years. In some cases, MAOIs may be prescribed to treat depression when newer ...
Of the estimated 16 million "long term" (over 24 months) users, roughly 70 percent are female. [301] As of 2017, about 16.5% of white people in the United States took antidepressants compared with 5.6% of black people in the United States. [302] Structural formula of the SSRI sertraline
For example, discontinuation of paroxetine in mice leads to anxiety-like behavior, together with a rebound over-activation of 5-HT neurons. [28] One problem is that many animal studies use fluoxetine as the study drug, despite it being not very commonly associated with withdrawal in human patients.
Martin Kingston told BBC Radio 4’s Today programme that he believed more people should be told explicitly the potential side effects of SSRIs and what can happen if they stop taking them.
[181] [182] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from the body. One strategy for minimizing SSRI discontinuation symptoms is to switch the patient to fluoxetine and then taper and discontinue the fluoxetine.
Overall, our findings suggest that more people over 70 years of age should be considered for statin treatment.” — Borislava Mihaylova, DPhil “Cardiovascular disease remains a leading cause ...
The most common side effects include nausea/vomiting, sweating, loss of appetite, dizziness, headache, increase in suicidal thoughts, and sexual dysfunction. [70] Elevation of norepinephrine levels can sometimes cause anxiety, mildly elevated pulse, and elevated blood pressure.