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A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
Metabolic bone disease is an abnormality of bones caused by a broad spectrum of disorders. Most commonly these disorders are caused by deficiencies of minerals such as calcium, phosphorus, magnesium or vitamin D leading to dramatic clinical disorders that are commonly reversible once the underlying defect has been treated.
Carpenter syndrome has been associated with mutations in the RAB23 gene, [7] which is located on chromosome 6 in humans. Additionally, three key SNPs in the MEGF8 gene, [8] located on chromosome 19 at 19q13.2, have been identified as primary causes of Carpenter syndrome.
It can take months or years to notice symptoms of type 1 diabetes. However, when they do come on, they can be sudden and severe. Causes of Type 2 Diabetes. When someone says they have diabetes, it ...
While certain kinds of diabetes, like type 1 diabetes, can come on quickly, the most common type—type 2 diabetes—can be a slower process. People with excess weight and a sedentary lifestyle ...
Individuals may have more or fewer bones than the average (even accounting for developmental stage) owing to anatomical variations. The most common variations include sutural (wormian) bones , which are located along the sutural lines on the back of the skull, and sesamoid bones which develop within some tendons, mainly in the hands and feet.
So far as macrovascular disease in type 1 diabetes is concerned, the same group reported improved outcomes for cardiovascular events in the group who had been managed by strict blood glucose control: in this group the incidence of any cardiovascular disease was reduced by 30% (95% CI 7, 48; P = 0.016) compared to the group with less intensive ...
Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).