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If arsenic poisoning occurs over a brief period of time, symptoms may include vomiting, abdominal pain, encephalopathy, and watery diarrhea that contains blood. [1] Long-term exposure can result in thickening of the skin, darker skin , abdominal pain, diarrhea, heart disease , numbness , and cancer .
The high affinity of arsenic for sulfhydryl groups makes keratin-rich cells (e.g., epidermal keratinocytes) a sensitive target for arsenic-induced toxicity. Arsenic has been shown to alter epidermal keratinocyte differentiation processes, [ 10 ] induce overexpression of growth factors , [ 11 ] and enhance proliferation of human keratinocytes.
Research has not been conducted to determine whether small amounts of arsenic may play a role in human metabolism. [17] [18] However, arsenic poisoning occurs in multicellular life if quantities are larger than needed. Arsenic contamination of groundwater is a problem that affects millions of people across the world.
According to WHO, short-term signs of arsenic poisoning include: Vomiting. Diarrhea. Stomach pain. Muscle cramping. Exposure to elevated levels of inorganic arsenic can be particularly dangerous ...
Man, 30, diagnosed with colon cancer after feeling stomach pain. Doctors explain colorectal cancer symptoms in younger people, how to self advocate. Chef, 30, was told his stomach pain was food ...
Colchicine poisoning has been compared to arsenic poisoning; symptoms typically start two to five hours after a toxic dose has been ingested but may take up to 24 hours to appear, and include burning in the mouth and throat, fever, vomiting, diarrhea, abdominal pain, and kidney failure. Onset of multiple-system organ failure may occur within 24 ...
The first breakthrough in the detection of arsenic poisoning was in 1775 when Carl Wilhelm Scheele discovered a way to change arsenic trioxide to garlic-smelling arsine gas (AsH 3), by treating it with nitric acid (HNO 3) and combining it with zinc. [3] As 2 O 3 + 6 Zn + 12 HNO 3 → 2 AsH 3 + 6 Zn(NO 3) 2 + 3 H 2 O
Generalised symptoms also include restlessness, weakness, hypothermia and low blood pressure. It is possible that Lewisite is carcinogenic: arsenic is categorized as a respiratory carcinogen by the International Agency for Research on Cancer, though it has not been confirmed that lewisite is a carcinogen. [12]