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Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
The development of selective 5-HT 3 receptor antagonists was a dramatic improvement in the treatment of nausea and vomiting. [30] Ondansetron, granisetron, dolasetron and palonosetron are currently approved in the United States, and form the cornerstone of therapy for the control of acute emesis with chemotherapy agents with moderate to high ...
C max is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administered and before the administration of a second dose. [1] It is a standard measurement in pharmacokinetics.
Shortly after Merck initiated research into reducing the severity and likelihood of chemotherapy-induced nausea and vomiting, researchers discovered that aprepitant is effective in prevention. Researchers worked on coming up with a process to create aprepitant, and within a short period they came up with effective synthesis of the substance.
The Gesell Developmental Schedules claimed that an appraisal of the developmental status of infants and young children could be made. The Gesell Developmental Schedule believes that human development unfolds in stages, or in sequences over a given time period. These stages were considered milestones, or the manifestations of mental development. [1]
The age of onset is the age at which an individual acquires, develops, or first experiences a condition or symptoms of a disease or disorder. For instance, the general age of onset for the spinal disease scoliosis is "10-15 years old," [ 1 ] meaning that most people develop scoliosis when they are of age between ten and fifteen years.
Divide the stimulus period or observation period T into N bins of size . Count the number of spikes k i from all n sequences that fall in the bin i . Draw a bar-graph histogram with the bar-height of bin i given by k i n Δ {\displaystyle {\frac {k_{i}}{n\Delta }}} in units of estimated spikes per second at time i Δ {\displaystyle i\ \Delta } .
An epidemic curve, also known as an epi curve or epidemiological curve, is a statistical chart used in epidemiology to visualise the onset of a disease outbreak. It can help with the identification of the mode of transmission of the disease. It can also show the disease's magnitude, whether cases are clustered or if there are individual case ...