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The P300 (P3) wave is an event-related potential (ERP) ... The signal is typically measured most strongly by the electrodes covering the parietal lobe.
In addition, there are studies on abnormalities of P300 in depression. Depressed patients tend to have a reduced P200 and P300 amplitude and a prolonged P300 latency. [20] Due to the consistency of the P300 response to novel stimuli, a brain–computer interface can be constructed which relies on it. By arranging many signals in a grid ...
P300 may mean: P300 (neuroscience), a neural evoked potential component of the electroencephalogram (EEG) p300 (or EP300), a transcriptional coactivator;
A P300 wave, including a P3b, is generated when the brain receives information that indicates that it needs to change these hypotheses, or update its mental model of the world. In other words, a P300 is elicited whenever there is sufficient information to indicate that the brain needs to update working memory. [3]
The p300-CBP coactivator family in humans is composed of two closely related transcriptional co-activating proteins (or coactivators): p300 (also called EP300 or E1A binding protein p300) CBP (also known as CREB-binding protein or CREBBP) Both p300 and CBP interact with numerous transcription factors and act to increase the expression of their ...
Cbp/p300-interacting transactivator 1 is a protein that in humans is encoded by the CITED1 gene. [5] [6] [7] Interactions.
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p300 HAT functions as histone acetyltransferase [6] that regulates transcription via chromatin remodeling, and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. p300 HAT contains a bromodomain which is involved in IL6 signaling. [7]: 3.1