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Endorphin production can be triggered by vigorous aerobic exercise. The release of β-endorphin has been postulated to contribute to the phenomenon known as "runner's high". [40] [41] However, several studies have supported the hypothesis that the runner's high is due to the release of endocannabinoids rather than that of endorphins. [42]
Endorphins are credited as the cause of the feeling of euphoria and wellbeing found in many forms of exercise, so proponents of this theory believe that the second wind is caused by their early release. [13] Many of these proponents feel that the second wind is very closely related to—or even interchangeable with—the runner's high. [14]
β-Endorphin release in response to exercise has been known and studied since at least the 1980s. [21] Studies have demonstrated that serum concentrations of endogenous opioids, in particular β-endorphin and β-lipotropin , increase in response to both acute exercise and training. [ 21 ]
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Proponents of dopamine fasting see a benefit from taking periodic breaks from technologies which are seen as addictive, such as smartphones. Dopamine fasting is the general practice of "fasting" or abstaining from any impulsive and behavioral addictions in order to cope with such addictions and thus attempt to reset to a healthier lifestyle.
Endogenous opiates include endorphins, enkephalins, dynorphins, and endomorphins. [ 5 ] Transcription and translation of opiate-encoding genes results in the formation of pre-propeptide opiate precursors, which are modified in the endoplasmic reticulum to become propeptide opiate precursors, transferred to the golgi apparatus , and further ...
In turn, the ventral tegmental area (VTA) is sensitive to 5-HT and NE release. [3] In the case of SSRIs, the promiscuity among transporters means that there may be more than a single type of neurotransmitter to consider (e.g. 5-HT, DA, NE, etc.) as mediating the therapeutic actions of a given medication.
It can also boost the immune system and release endorphins to relieve pain. [33] Additionally, laughter can help prevent heart disease by increasing blood flow and improving the function of blood vessels. [34] Some of the emotional benefits include diminishing anxiety or fear, improving overall mood, and adding joy to one's life.