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Serious side effects include excessive breakdown of red blood cells, increased risk of suicide, severe skin reaction (Stevens–Johnson syndrome), and allergic reactions, which can be fatal. [8] Lamotrigine is a phenyltriazine, [5] making it chemically different from other anticonvulsants. [8]
Sexual side effects are also common with SSRIs, such as loss of sexual drive, failure to reach orgasm, and erectile dysfunction. [157] Although usually reversible, these sexual side-effects can, in rare cases, continue after the drug has been completely withdrawn. [158] [159]
Management strategies include: for erectile dysfunction the addition of a PDE5 inhibitor such as sildenafil; for decreased libido, possibly adding or switching to bupropion; and for overall sexual dysfunction, switching to nefazodone. [53] Buspirone is sometimes used off-label to reduce sexual dysfunction associated with the use of SSRIs. [54 ...
Erectile dysfunction can cause a “self-perpetuating cycle of anxiety and performance pressure,” says one expert. (Photo illustration: Victoria Ellis for Yahoo News; photo: Getty Images) (Photo ...
Focused shockwave therapy appears to work best for males with vasculogenic ED, which is a blood vessel disorder that affects blood flow to tissue in the penis. The treatment is painless and has no known side effects. Treatment with shockwave therapy can lead to a significant improvement of the IIEF (International Index of Erectile Function).
A common cause of anorgasmia, in both women and men, is the use of antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs). Though reporting of anorgasmia as a side effect of SSRIs is not precise, studies have found that 17–41% of users of such medications are affected by some form of sexual dysfunction.
Some anticonvulsants such as gabapentin may even lead to discomfort in the gastrointestinal system, such as constipation and diarrhoea. For valproic acid, more severe adverse effects like hepatic dysfunction may be caused. Signs include persistent vomiting, abdominal pain, anorexia, jaundice, oedema and loss of seizure control.
Unlike other SSRIs used to treat depression, which have been associated with high incidences of sexual dysfunction, [19] dapoxetine is associated with low rates of sexual dysfunction. Taken as needed, dapoxetine has very mild adverse effects of decreased libido (<1%) and erectile dysfunction (<4%). [7]
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