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TORCH syndrome is a cluster of symptoms caused by congenital infection with toxoplasmosis, rubella, cytomegalovirus, herpes simplex, and other organisms including syphilis, parvovirus, and Varicella zoster. [1] Zika virus is considered the most recent member of TORCH infections. [2]
A vertically transmitted infection is an infection caused by pathogenic bacteria or viruses that ... The TORCH complex was originally considered to consist of the ...
Toxoplasmosis: TORCH infection due to Toxoplasma gondii parasite. Condition is commonly associated with undercooked meat or contact with cat feces. Symptoms of this disease include seizures, hydrocephalus, and chorioretinitis. Cytomegalovirus: viral TORCH infection associated with sensorineural hearing loss, hepatomegaly, and jaundice.
If the fetus survives the infection, it can be born with severe heart disorders (patent ductus arteriosus being the most common), blindness, deafness, or other life-threatening organ disorders. The skin manifestations are called "blueberry muffin lesions". [18] For these reasons, rubella is included in the TORCH complex of perinatal infections ...
To some extent, acute toxoplasmosis infections can be differentiated from chronic infections using an IgG avidity test, which is a variation on the ELISA. In the first response to infection, toxoplasma-specific IgG has a low affinity for the toxoplasma antigen; in the following weeks and month, IgG affinity for the antigen increases.
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For many infections, the baby is more at risk at particular stages of pregnancy. Problems related to perinatal infection are not always directly noticeable. [citation needed] The term TORCH complex refers to a set of several different infections that may be caused by transplacental infection: T - Toxoplasmosis