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Pilocarpine stimulates the secretion of large amounts of saliva and sweat. [16] It is used to prevent or treat dry mouth, particularly in Sjögren syndrome, but also as a side effect of radiation therapy for head and neck cancer. [17] It may be used to help differentiate Adie syndrome from other causes of unequal pupil size. [18] [19]
Xerostomia is a very common symptom. A conservative estimate of prevalence is about 20% in the general population, with increased prevalences in females (up to 30%) and the elderly (up to 50%). [8] Estimates of the prevalence of persistent dry mouth vary between 10 and 50%. [8]
Patients can lessen the effects of xerostomia with breath mints, sugarless gum, or lozenges; or physicians can increase saliva flow with artificial saliva or oral pilocarpine. [39] Artificial saliva mimics the characteristics of natural saliva by lubricating and protecting the mouth, but does not provide any digestive or enzymatic benefits. [ 40 ]
The following are used in dentistry to treat xerostomia: [3] Parasympathomimetic drugs act on parasympathetic muscarinic receptors to induce an increased saliva flow. The M3 receptor has been identified as the principal target to increase salivary flow rates. [4] Pilocarpine is an example; the maximum dose of this drug is 30 mg/day ...
It is used in the treatment of dry mouth and Sjögren's syndrome. Medical uses ... Pilocarpine — a similar parasympathomimetic medication for dry mouth ...
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Sjögren syndrome (an early symptom in some patients) [8] Medications that can cause overproduction of saliva include: [4] aripiprazole; clozapine; pilocarpine; ketamine; potassium chlorate; risperidone; pyridostigmine; Substances that can cause hypersalivation include: [4] mercury; copper; organophosphates (insecticide) arsenic; nicotine; thallium
When it comes to losing weight, there are no shortage of unproven recommendations to choose from: fad diets like the carnivore diet or GOLO diet; juice cleanses and vitamin injections; plus a host ...
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related to: pilocarpine worsening xerostomia in elderly patients mayo clinic information- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
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