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"Time to peak" refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic, sedative, hypnotic, skeletal muscle relaxant, amnesic, and anticonvulsant effects. Variation in potency of certain effects may exist amongst individual ...
Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. [15] It is used to treat a range of conditions, including anxiety , seizures , alcohol withdrawal syndrome , muscle spasms , insomnia , and restless legs syndrome . [ 15 ]
Midazolam 1 & 5 mg/mL injections (Canada). Benzodiazepines possess psycholeptic, sedative, hypnotic, anxiolytic, anticonvulsant, muscle relaxant, and amnesic actions, [4] [5] which are useful in a variety of indications such as alcohol dependence, seizures, anxiety disorders, panic, agitation, and insomnia.
Librium, based on the R0 6-690 compound discovered by Sternbach in 1956, was approved for use in 1960. In 1963, its improved version, Valium, was released and became astonishingly popular: between 1969 and 1982, it was the most prescribed drug in America, with over 2.3 billion doses sold in its peak year of 1978.
Dion, who was taking Valium so she could perform, gradually built a tolerance and at one point was taking 90 milligrams a day — far beyond the maximum recommended dosage of 40 milligrams ...
Dion, a five-time Grammy winner, said that to control symptoms, she started with 20-milligram doses of the powerful medication, which can curb muscle spasms and seizures. Adult doses typically a ...
Céline Dion revealed she would take up to 90mg of Valium per day to ease her stiff-person syndromes in her first TV interview since her diagnosis. "We tried a lot of things. Trying a lot of ...
Valium 15 November 1963 [55] divalproex sodium: Depakote 10 March 1983 [56] eslicarbazepine: Aptiom 11 August 2013 [57] [58] ethosuximide: Zarontin 2 November 1960 [59] 1955 [46] 1962 [51] ethotoin: Peganone 22 April 1957 [60] everolimus: Afinitor/Votubia 30 January 2009 [61] felbamate: Felbatol