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The economic history of the Philippines is shaped by its colonial past, evolving governance, and integration into the global economy. Prior to Spanish colonization in the 16th century, the islands had a flourishing economy centered around agriculture, fisheries, and trade with neighboring countries like China, Japan, and Southeast Asia.
Alanine (symbol Ala or A), [4] or α-alanine, is an α-amino acid that is used in the biosynthesis of proteins. It contains an amine group and a carboxylic acid group, both attached to the central carbon atom which also carries a methyl group side chain. Consequently it is classified as a nonpolar, aliphatic α-amino acid.
The Indian influences in early Philippine polities, particularly the influence of the Srivijaya and Majapahit thalassocracies on cultural development, is a significant area of research for scholars of Philippine, Indonesian, and Southeast Asian history, [1] and is believed to be the source of Hindu and Buddhist elements in early Philippine culture, religion, and language.
Figure 3. Schematic diagram of the distance between Lys39, Tyr 265, and PLP-L-Ala in the active site. All interactions shown are under 4.5 and therefore are capable of hydrogen bonding. Adapted from Watanabe et al. Based on the crystal structures of N-(5’-phosphopyridoxyl) L- alanine (PKP-L-Ala ( and N-(5’-phosphopyridoxyl) D-alanine (PLP-D ...
L-amino acids are the mirror reflection of D-amino acids, and vice versa. In this example, alanine is depicted in the zwitterionic form at physiological pH. D-Amino acids are amino acids where the stereogenic carbon alpha to the amino group has the D-configuration. For most naturally-occurring amino acids, this carbon has the L-configuration.
[11]: 41 Spanish served as a common language for the growing local elite, who shared a Western educational background despite varied ethnolinguistic origins. Most came from Manila. [12]: 2, 30 A class of educated individuals became known as the Ilustrados. This group included individuals who had studied at both local universities and Spanish ...
β-Alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available β-alanine, not histidine. [6] Supplementation with β-alanine has been shown to increase the concentration of carnosine in muscles, decrease fatigue in athletes, and increase total muscular work done.
The fourth societal category above can be termed the datu class, and was a titled aristocracy. [5]: 150–151 The early polities were typically made up of three-tier social structure: a nobility class, a class of "freemen", and a class of dependent debtor-bondsmen: [6] [7] Datu (ruling class) and Maginoo (noble class, where the datu ascends from)