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2. Metformin - Wikipedia

   en.wikipedia.org/wiki/Metformin

   The US Food and Drug Administration (FDA) recommends avoiding the use of metformin in more severe chronic kidney disease, below the eGFR cutoff of 30 mL/minute/1.73 m 2. [94] Lactate uptake by the liver is diminished with metformin use because lactate is a substrate for hepatic gluconeogenesis, a process that metformin inhibits.

3. Is There a "Best Time" to Take Metformin? - AOL

   www.aol.com/best-time-metformin-115700262.html

   Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin tablets ...

4. Why Doctors Are Calling This Common Medication a "Wonder Drug"

   www.aol.com/why-doctors-calling-common...

   That said, “it's important to note, if you have kidney disease or reduced kidney function, you should either not take metformin or take this drug under supervision by a healthcare professional ...

5. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

   www.aol.com/diabetes-drugs-really-safe-reliable...

   A 2020 meta-analysis of 21 metformin trials found the drug had a clinically significant impact on lowering BMI — particularly in folks with obesity. ... Kidney disease. Pancreatitis.

6. Gliclazide - Wikipedia

   en.wikipedia.org/wiki/Gliclazide

   It is used when diabetes cannot be controlled by proper dietary management and exercise and when metformin has already been tried. [11] National Kidney Foundation (2012 Update) claims that Gliclazide does not require dosage up titration even in end stage kidney disease.

7. Kidney failure - Wikipedia

   en.wikipedia.org/wiki/Kidney_failure

   Kidney failure can be divided into two categories: acute kidney failure or chronic kidney failure. The type of renal failure is differentiated by the trend in the serum creatinine ; other factors that may help differentiate acute kidney failure from chronic kidney failure include anemia and the kidney size on sonography as chronic kidney ...

8. Diabetes in Men: What You Need to Know - AOL

   www.aol.com/diabetes-men-know-115800086.html

   Heart disease. Chronic kidney disease. ... Metformin is one of the most common first-line medications for type 2 diabetes. Side effects of diabetes medications can include weight loss.

9. Diabetic nephropathy - Wikipedia

   en.wikipedia.org/wiki/Diabetic_nephropathy

   Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria ...