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The Semmes-Weinstein Aesthesiometer, and its variant the Weinstein Enhanced Sensory Test (WEST, e.g., WEST-hand), present nylon monofilaments of approximately the same length (38 mm) and of varying diameters. The diameter and length are used to control the force applied.
The most useful physical examination finding for large fiber neuropathy is an abnormally decreased vibration perception to a 128-Hz tuning fork (likelihood ratio (LR) range, 16–35) or pressure sensation with a 5.07 Semmes-Weinstein monofilament (LR range, 11–16).
It is unclear whether the process is really considered noxious versus simply annoying, so this assay is a test of mechanical nociception or simply mechanical sensibility. In this test, the animal stands on an elevated mesh platform, and the Von Frey hairs are inserted through the mesh to poke the animal’s hindpaw. [2]
Diminished threshold sensibility (the ability to distinguish different amounts of pressure) can be measured using Semmes-Weinstein monofilament testing. [37] Diminished discriminant sensibility can be measured by testing two-point discrimination: the number of millimeters two points of contact need to be separated before you can distinguish them.
A neurological examination is the assessment of sensory neuron and motor responses, especially reflexes, to determine whether the nervous system is impaired. This typically includes a physical examination and a review of the patient's medical history, [1] but not deeper investigation such as neuroimaging.
QST relies on analysis of a patient's response to external stimuli of controlled intensity. A stimulus is applied to the skin of the nerve area being tested in ascending and descending orders of magnitude. Clinicians can quantify the mechanical sensitivity of the tactile stimulus using von Frey hairs or Semmes-Weinstein monofilaments (SWMFs ...
The characteristic of the sensory reinnervation was quantified. Light touch is quantified by a threshold determined with Semmes-Weinstein monofilaments (a sensation measurement instrument). [2] A Neurotip neurometer was used to determine the sensibility of sharpness and dullness at 20 sites distributed throughout the targeted muscle (the chest ...
A monofilament may refer to: Monofilament fishing line, a type of thread; A monofilament as used in a monofilament test in a neurological examination; Monomolecular wire, a theoretical type of wire consisting of a single strand of molecules