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  2. Gastrointestinal stromal tumor (GIST) - Overview - Mayo Clinic

    www.mayoclinic.org/diseases-conditions/gastrointestinal...

    Gastrointestinal stromal tumor (GIST) A gastrointestinal stromal tumor (GIST) is a type of cancer that begins in the digestive system. ... By blocking these chemicals, targeted drug treatments can cause cancer cells to die. For GISTs, the target of these drugs is an enzyme called tyrosine kinase that helps cancer cells grow.

  3. What Causes Gastrointestinal Stromal Tumors? - American Cancer...

    www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/...

    Researchers do not know exactly what causes most gastrointestinal stromal tumors (GISTs). But great progress has been made in learning how certain changes in DNA can cause normal cells to become cancer cells. DNA is the chemical in our cells that makes up our genes, which control how our cells function. We usually look like our parents because ...

  4. Gastrointestinal stromal tumors (GISTs): What are they, and how...

    www.mdanderson.org/cancerwise/gastrointestinal-stromal...

    A gastrointestinal stromal tumor, also called a GIST, is a type of sarcoma that develops in the connective tissue of the gastrointestinal tract. ... meaning there’s no known cause. They often start as one tumor. In rare cases, people can be prone to developing multiple tumors at a younger age, or multiple family members can have a GIST.

  5. Gastrointestinal Stromal Tumor (GIST) - Cleveland Clinic

    my.clevelandclinic.org/health/diseases/17031

    Gastrointestinal stromal tumors (GISTs) may not cause noticeable symptoms. But when they do, you might blame your upset stomach on a recent meal or maybe the stomach flu. It may come as a shock to learn a rare cancerous tumor is why you don’t feel well. If you have this condition, take some time to learn about this rare disease, including ...

  6. Gastrointestinal Stromal Tumors (GIST) > Fact Sheets - Yale...

    www.yalemedicine.org/conditions/gastrointestinal-stromal...

    A gastrointestinal stromal tumor (sometimes called a “GIST”) is an uncommon type of cancer that forms in cells of the digestive tract wall. Between 4,000 to 6,000 people are diagnosed with gastrointestinal stromal tumors each year in the United States, according to the American Cancer Society.

  7. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal (GI) tract, accounting for 80% of all such GI tumors, and 0.1 to 3% of all gastrointestinal malignancies.[1] ... the differential diagnoses would include other causes of intraabdominal malignancy. In patients found to have subepithelial mass ...

  8. Gastrointestinal Stromal Tumor Causes, Risk Factors, and...

    www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/...

    The only known risk factors for gastrointestinal stromal tumors (GISTs) − older age and certain rare, inherited genetic syndromes – cannot be changed. There are no known lifestyle-related or environmental causes of GISTs, so at this time we do not know of any way to protect against these cancers.

  9. GIST: Risk Factors, Causes, & Symptoms - Healthline

    www.healthline.com/health/gist/risk-factors-causes-and...

    Gastrointestinal stromal tumors (GISTs) form in the walls of the gastrointestinal tract, predominantly in the stomach or small intestine. Learn who's at risk, what causes these tumors, and common ...

  10. If You Have a Gastrointestinal Stromal Tumor (GIST)

    www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/...

    How does the doctor know I have a GIST? Many GISTs don’t cause symptoms right away. Sometimes they are found when a person has an exam or test done for another problem. If a GIST does cause symptoms, they might include throwing up blood, or having bloody or dark colored stools. They might also cause belly pain, loss of appetite, or weight loss.

  11. GIST (Gastrointestinal Stromal Tumor) - Memorial Sloan Kettering ...

    www.mskcc.org/.../types/gist-gastrointestinal-stromal-tumor

    A gastrointestinal stromal tumor (GIST) is a rare cancer. It is a type of soft tissue sarcoma that often begins in the abdomen. Before 1998, doctors classified GIST as leiomyosarcoma, gastrointestinal autonomic nerve tumor (GANT), or a combination of those two tumor types.. GISTs are often found during an endoscopy or CT scan for an unrelated condition.

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