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Hyperhidrosis is a medical condition in which a person exhibits excessive sweating, [1] [2] more than is required for the regulation of body temperature. [3] Although it is primarily a physical burden, hyperhidrosis can deteriorate the quality of life of the people who are affected from a psychological, emotional, and social perspective. [4]
Focal hyperhidrosis, also known as primary hyperhidrosis, is a disease characterized by an excessive sweating localized in certain body regions (particularly palms, feet and underarms). Studies suggest that this condition, affecting between 1% and 3% of the US population, seems to have a genetic predisposition in about two thirds of those affected.
Glycopyrronium tosylate, sold under the brand name Qbrexza among others, is a medication used for the treatment of primary axillary hyperhidrosis. [1] [2] [3] It was approved for medical use in the United States in June 2018, [4] and in Japan in January 2022. [5]
Sofpironium bromide, sold under the brand name Ecclock among others, is a medication used to treat hyperhidrosis (excessive sweating). [1] Sofpironium bromide is an anticholinergic agent that is applied to the skin. [1] It was approved in Japan in 2020, for the treatment of primary axillary hyperhidrosis. [2]
Hyperhidrosis is usually brought on by emotional or thermal stress, [64] but it can also occur or with little to no stimulus. [60] Local (or asymmetrical) hyperhidrosis is said to be caused by problems in the sympathetic nervous system: either lesions [64] or nerve inflammation. [65] Hyperhidrosis can also be caused by trench foot or ...
Hyperhidrosis is excessive sweating, usually secondary to an underlying condition (in which case it is called secondary hyperhidrosis) and usually involving the body as a whole (in which case it is called generalized hyperhidrosis). [13] Hidromeiosis is a reduction in sweating that is due to blockages of sweat glands in humid conditions. [14]
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