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While serum iron levels can tell you how much total iron is in your blood, iron saturation tells you how much you’re actually absorbing. When people discuss anemia (low iron) or hemochromatosis (high iron), they’re actually talking about iron saturation more than total iron levels in the blood.
Doctors often test for low iron levels if hemoglobin is low and consistent with anemia. The normal range of iron saturation can vary from person to person, and it can change over time...
The transferrin saturation is the ratio of serum iron to the TIBC, expressed as a percentage. Levels fall in both iron deficiency and inflammatory anaemia. The table below summarises the changes in the various laboratory indicies in different disease states:
The two key tests to detect iron overload are: Serum transferrin saturation. This test measures the amount of iron bound to the protein transferrin that carries iron in your blood. Transferrin saturation values greater than 45% are considered too high. Serum ferritin. This test measures the amount of iron stored in your liver.
Transferrin saturation, abbreviated TS and measured as a percentage, is the ratio of serum iron and total iron-binding capacity (TIBC). TS is a more useful indicator of iron status than just iron or TIBC alone.
Transferrin saturation (TS), measured as a percentage, is a medical laboratory value. It is the value of serum iron divided by the total iron-binding capacity [1] of the available transferrin, the main protein that binds iron in the blood, this value tells a clinician how much serum iron is bound.
Increased transferrin saturation can be caused by: Iron-rich diet; Iron supplements; Increased iron absorption (e.g., primary hemochromatosis); and; Repeated blood transfusions. A saturation value higher than the reference range indicates that you have too much iron in your body.
Transferrin saturations of less than 20% indicate iron deficiency, while transferrin saturations of more than 50% suggest iron overload. The terms transferrin saturation and iron-binding...
Iron deficiency (ID) is defined as the decrease of the total content of iron in the body. Iron deficiency anemia (IDA) occurs when ID is sufficiently severe to reduce erythropoiesis. This type of anemia is the most frequent chronic anemia.
Total serum iron: 26–170 mcg/dL in women and 76–198 mcg/dL in men; Transferrin saturation: 204–360 mg/dL; Abnormal ranges. The serum iron test and other related tests may reveal low or high...