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[23] [3] It is classified as a sensory ganglionopathy due to involvement of these ganglia. [ 61 ] [ b ] In electrodiagnostic testing , it has characteristic non-length-dependent abnormalities of sensory action potentials that occur globally, rather than distally decreasing sensory nerve action potential amplitudes. [ 57 ]
The causes of nerve damage are grouped into categories including those due to paraneoplastic causes (neuropathy secondary to cancer), immune mediated, infectious, inherited or degenerative causes and those due to toxin exposure. In idiopathic sensory neuronopathy no cause is identified. Idiopathic causes account for about 50% of cases. [2]
Peripheral mononeuropathy is a nerve related disease where a single nerve, that is used to transport messages from the brain to the peripheral body, is diseased or damaged. [1] Peripheral neuropathy is a general term that indicates any disorder of the peripheral nervous system . [ 2 ]
Damage to the sensory nerve causes a wide range of symptoms because of the number of functions performed by the nerve. Traumatic injuries and other damages to the sensory nerves may lead to peripheral neuropathy, with problems such as reduced position sense causing poorer coordination and balance, in addition to reduced sensitivity to temperature change and pain, leading to further problems.
Denervation can occur as a consequence of nerve injury. The three primary categories of nerve injury are neurapraxia, axonotmesis, and neurotmesis, each corresponding to varying degrees of damage and potential for recovery. In cases of nerve injury, the brain demonstrates an impressive ability to rewire or reorganize its neuronal circuitry ...
Existing treatments aim to suppress the immune system to prevent further damage to nerve cells. ... shows that PIPE-307 has the potential to be used as a myelin repair treatment. But to really ...
sensory and visual neglect syndromes, i.e. inability to pay attention to things in certain parts of the person's sensory or spatial environment; this may be as extreme as denial of a limb; loss of ability to read, write, or calculate (dyslexia, dysgraphia, dyscalculia) loss of ability to find a defined place (geographical agnosia)
It was noted that after 3 weeks, a mixed nerve defect had undergone substantial regeneration when paired with a motor nerve graft or a mixed nerve graft. In comparison, a sensory nerve graft was statistically less affective in regeneration, looking specifically at nerve fiber count, percent nerve, and nerve densities as the main three ...