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Drug coupons reduce out-of-pocket costs for consumers in a variety of ways such as instant savings offers, free trial offers (also known as try-before-you-buy offers), copay reduction or rebates. Generic drug companies rarely offer coupons, though insurance companies occasionally offer discounts on generic drugs.
Ephedrine works by inducing the release of norepinephrine and hence indirectly activating the α-and β-adrenergic receptors. [11] Chemically, ephedrine is a substituted amphetamine and is the (1R,2S)-enantiomer of β-hydroxy-N-methylamphetamine. [14] Ephedrine was first isolated in 1885 and came into commercial use in 1926.
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Ephedrine, pseudoephedrine, and phenylpropanolamine are precursor chemicals used in the illicit manufacture of methamphetamine or amphetamine. They are also common ingredients used to make cough, cold, and allergy products. It was argued that the CMEA would curtail the clandestine production of methamphetamine.
Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1] It is taken by mouth. [1] It was approved for medical use in the United States in 2006. [1]
[3] [4] [5] However, at high dose, it may lead to cardiac arrhythmias, hypertension, seizures or other serious cardiovascular and/or central nervous system adverse effects. [6] [7] [8] Tedral is contraindicated in individuals with hypersensitivity to theophylline, ephedrine and/or phenobarbital.
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