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Deaths. 0. Uhthoff's phenomenon (also known as Uhthoff's syndrome, [ 1] Uhthoff's sign, [ 1] and Uhthoff's symptom) is the worsening of neurologic symptoms in multiple sclerosis (MS) and other demyelinating diseases when the body is overheated. This may occur due to hot weather, exercise, fever, saunas, hot tubs, hot baths, and hot food and drink.
Wilhelm Uhthoff. Wilhelm Uhthoff (31 July 1853 – 21 March 1927) was a German ophthalmologist born in Klein-Warin . In 1877 earned his doctorate at the University of Berlin, and later became a professor of ophthalmology at the Universities of Marburg (1890) and Breslau (1896), where he succeeded Carl Friedrich Richard Förster (1825–1902).
Optic neuritis describes any condition that causes inflammation of the optic nerve; it may be associated with demyelinating diseases, or infectious or inflammatory processes. [ 1] It is also known as optic papillitis (when the head of the optic nerve is involved), neuroretinitis (when there is a combined involvement of the optic disc and ...
Frequency. Up to 1 in 10,000 [ 1] Neuromyelitis optica spectrum disorders ( NMOSD) are a spectrum of autoimmune diseases characterized by acute inflammation of the optic nerve ( optic neuritis, ON) and the spinal cord ( myelitis ). [ 1][ 2][ 3] Episodes of ON and myelitis can be simultaneous or successive.
Another promising MRI technique is magnetic transfer imaging, which will allow the detection of damage in normal-appearing brain tissue away from focal lesions. Finally, high resolution spectral domain optical coherence tomography could prove to be a very promising and sensitive way of identifying optic neuritis in the future. [5]
The myelinoclastic disorders are typically associated with symptoms such as optic neuritis and transverse myelitis, because the demyelinating inflammation can affect the optic nerve or spinal cord. Many are idiopathic. Both myelinoclastic and leukodystrophic modes of disease may result in lesional demyelinations of the central nervous system.
The Pulfrich effect has been utilized to enable a type of stereoscopy, or 3-D visual effect, in visual media such as film and TV. As in other kinds of stereoscopy, glasses are used to create the illusion of a three-dimensional image. By placing a neutral filter (e.g., the darkened lens from a pair of sunglasses) over one eye, an image, as it ...
Diroximel fumarate, sold under the brand name Vumerity, is a medicationused for the treatment of relapsing forms of multiple sclerosis(MS). [3][5][6]It acts as an immunosuppressantand anti-inflammatorydrug. Its most common adverse effects are flushingand gastrointestinalproblems. [7]