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  2. Uhthoff's phenomenon - Wikipedia

    en.wikipedia.org/wiki/Uhthoff's_phenomenon

    Uhthoff's phenomenon (also known as Uhthoff's syndrome, [ 1] Uhthoff's sign, [ 1] and Uhthoff's symptom) is the worsening of neurologic symptoms in multiple sclerosis (MS) and other demyelinating diseases when the body is overheated. This may occur due to hot weather, exercise, fever, saunas, hot tubs, hot baths, and hot food and drink.

  3. Lhermitte's sign - Wikipedia

    en.wikipedia.org/wiki/Lhermitte's_sign

    Compression of the upper spinal cord, multiple sclerosis, transverse myelitis, Behçet's disease, osteogenesis imperfecta. In neurology, Lhermitte phenomenon, also called the barber chair phenomenon, is an uncomfortable "electrical" sensation that runs down the back and into the limbs. The sensation can feel like it goes up or down the spine.

  4. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis is an autoimmune disease with a combination of genetic and environmental causes underlying it. Both T-cells and B-cells are involved, although T-cells are often considered to be the driving force of the disease. The causes of the disease are not fully understood.

  5. Mitochondrial DNA depletion syndrome - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_DNA...

    Mitochondrial DNA depletion syndrome ( MDS or MDDS ), or Alper's disease, is any of a group of autosomal recessive disorders that cause a significant drop in mitochondrial DNA in affected tissues. Symptoms can be any combination of myopathic, hepatopathic, or encephalomyopathic. [ 1] These syndromes affect tissue in the muscle, liver, or both ...

  6. Alexander disease - Wikipedia

    en.wikipedia.org/wiki/Alexander_disease

    Alexander disease is a very rare autosomal dominant leukodystrophy, which are neurological conditions caused by anomalies in the myelin which protects nerve fibers in the brain. The most common type is the infantile form that usually begins during the first two years of life. Symptoms include mental and physical developmental delays, followed ...

  7. CNS demyelinating autoimmune diseases - Wikipedia

    en.wikipedia.org/wiki/CNS_demyelinating...

    Causes. CNS demyelination autoimmune disease causes the myelin sheath to deteriorate since the sense of recognition of self is lost. The loss of the myelin insulation either disrupts or prevents neural conduction along the nerve cell's axon.

  8. Harlequin syndrome - Wikipedia

    en.wikipedia.org/wiki/Harlequin_syndrome

    Harlequin syndrome is a condition characterized by asymmetric sweating and flushing on the upper thoracic region of the chest, neck and face. Harlequin syndrome is considered an injury to the autonomic nervous system (ANS). The ANS controls some of the body's natural processes such as sweating, skin flushing and pupil response to stimuli. [ 1]

  9. Wilhelm Uhthoff - Wikipedia

    en.wikipedia.org/wiki/Wilhelm_Uhthoff

    Wilhelm Uhthoff. Wilhelm Uhthoff (31 July 1853 – 21 March 1927) was a German ophthalmologist born in Klein-Warin . In 1877 earned his doctorate at the University of Berlin, and later became a professor of ophthalmology at the Universities of Marburg (1890) and Breslau (1896), where he succeeded Carl Friedrich Richard Förster (1825–1902).