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Uhthoff's phenomenon (also known as Uhthoff's syndrome, [ 1] Uhthoff's sign, [ 1] and Uhthoff's symptom) is the worsening of neurologic symptoms in multiple sclerosis (MS) and other demyelinating diseases when the body is overheated. This may occur due to hot weather, exercise, fever, saunas, hot tubs, hot baths, and hot food and drink.
Compression of the upper spinal cord, multiple sclerosis, transverse myelitis, Behçet's disease, osteogenesis imperfecta. In neurology, Lhermitte phenomenon, also called the barber chair phenomenon, is an uncomfortable "electrical" sensation that runs down the back and into the limbs. The sensation can feel like it goes up or down the spine.
Wilhelm Uhthoff. Wilhelm Uhthoff (31 July 1853 – 21 March 1927) was a German ophthalmologist born in Klein-Warin . In 1877 earned his doctorate at the University of Berlin, and later became a professor of ophthalmology at the Universities of Marburg (1890) and Breslau (1896), where he succeeded Carl Friedrich Richard Förster (1825–1902).
Frequency. Up to 1 in 10,000 [ 1] Neuromyelitis optica spectrum disorders ( NMOSD) are a spectrum of autoimmune diseases characterized by acute inflammation of the optic nerve ( optic neuritis, ON) and the spinal cord ( myelitis ). [ 1][ 2][ 3] Episodes of ON and myelitis can be simultaneous or successive.
0.032% ( world) Multiple sclerosis ( MS) is an autoimmune disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. [ 3] This damage disrupts the ability of parts of the nervous system to transmit signals, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric ...
Pathophysiology (or physiopathology) is a branch of study, at the intersection of pathology and physiology, concerning disordered physiological processes that cause, result from, or are otherwise associated with a disease or injury. Pathology is the medical discipline that describes conditions typically observed during a disease state, whereas ...
Causes. CNS demyelination autoimmune disease causes the myelin sheath to deteriorate since the sense of recognition of self is lost. The loss of the myelin insulation either disrupts or prevents neural conduction along the nerve cell's axon.
Marchiafava–Bignami disease. This condition affects the corpus callosum. Specialty. Neurology. Marchiafava–Bignami disease is a progressive neurological disease of alcohol use disorder, characterized by corpus callosum demyelination and necrosis and subsequent atrophy. The disease was first described in 1903 by the Italian pathologists ...