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Peeling skin syndrome 5 is caused by a genetic defect in the serpin (serpin family member 8) gene. This gene is produced by platelets and can bind to and inhibit the function of furin, which is a serine protease involved in platelet functions.
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
Death usually occurs during early adulthood. Frequency. around 1 in 500,000 [ 5] Epidermolysis bullosa ( EB) is a group of rare medical conditions that result in easy blistering of the skin and mucous membranes. Blisters occur with minor trauma or friction and are painful. Its severity can range from mild to fatal. [ 7]
Topical steroid withdrawal, also known as red burning skin and steroid dermatitis, has been reported in people who apply topical steroids for 2 weeks or longer and then discontinue use. [ 4][ 5][ 2][ 1] Symptoms affect the skin and include redness, a burning sensation, and itchiness, [ 2] which may then be followed by peeling. [ 2]
Keratolysis exfoliativa (also known as" lamellar dyshidrosis ", [ 1] " recurrent focal palmar peeling ", [ 2] " recurrent palmar peeling " [ 1]: 212 [ 2]) is a sometimes harmless, sometimes painful skin condition that can affect the focal surface of the fingers and/or the palm or soles of the feet. It is often misdiagnosed as chronic contact ...
Toxic epidermal necrolysis ( TEN ), also known as Lyell's syndrome, is a type of severe skin reaction. [ 2] Together with Stevens–Johnson syndrome (SJS) it forms a spectrum of disease, with TEN being more severe. [ 2] Early symptoms include fever and flu-like symptoms. [ 2]
Specialty. Dermatology. Psychiatry. Excoriation disorder, more commonly known as dermatillomania, is a mental disorder on the obsessive–compulsive spectrum that is characterized by the repeated urge or impulse to pick at one's own skin, to the extent that either psychological or physical damage is caused. [ 4][ 5]
Skeeter syndrome. Skeeter syndrome (papular urticaria) is a localized severe allergic reaction to mosquito bites, [1] consisting of inflammation, peeling skin, blistering, ulceration and sometimes fever. It is caused by allergenic polypeptides in mosquito saliva, and therefore is not contagious. [2] It is one of several forms, being one of the ...