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Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [ 8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs). It is a reasonable initial treatment for high blood pressure. [ 8]
Valsartan/hydrochlorothiazide. Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient. [ 6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic. [ 7] It is taken by mouth.
Angiotensin II receptor blockers ( ARBs ), formally angiotensin II receptor type 1 (AT1) antagonists, [ 1] also known as angiotensin receptor blockers, [ 2][ 3] angiotensin II receptor antagonists, or AT1 receptor antagonists, are a group of pharmaceuticals that bind to and inhibit the angiotensin II receptor type 1 (AT 1) and thereby block the ...
Diovan HCT (valsartan and hydrochlorothiazide) Exforge HCT (amlodipine and hydrochlorothiazide) Hyzaar (losartan and hydrochlorothiazide) Lotensin HCT (benazepril and hydrochlorothiazide)
Hydrochlorothiazide. Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. [ 4] Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the ...
Losartan, valsartan, candesartan, irbesartan, telmisartan and olmesartan all contain a biphenyl-methyl group. Losartan is partly metabolized to its 5- carboxylic acid metabolite EXP 3174, which is a more potent AT 1 receptor antagonist than its parent compound [ 17 ] and has been a model for the continuing development of several other ARBs.
Drug-induced angioedema. Drug-induced angioedema is a known complication of the use of angiotensin-converting enzyme (ACE) inhibitors, angiotensin II antagonists (ARBs), and Angiotensin-Neprilysin Inhibitor LCZ969. [ 1]: 120 The angioedema appears to be dose dependent as it may resolve with decreased dose. [ 1]: 120.
Sacubitril/valsartan, sold under the brand name Entresto, is a fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan. The combination is sometimes described as an "angiotensin receptor-neprilysin inhibitor" (ARNi). [ 9]