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Platelet. Platelets or thrombocytes (from Ancient Greek θρόμβος (thrómbos) 'clot' and κύτος (kútos) 'cell') are a blood component whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. [ 1] Platelets have no cell nucleus; they are fragments ...
Thrombocytosis, meaning a high platelet count, may occur in states of inflammation or trauma, [163] as well as in iron deficiency, [164] and the platelet count may reach exceptionally high levels in people with essential thrombocythemia, a rare blood disease. [163] The platelet count can be reported in units of cells per microlitre of blood ...
Thrombocythemia. In hematology, thrombocythemia is a condition of high platelet (thrombocyte) count in the blood. Normal count is in the range of 150 × 10 9 to 450 × 10 9 platelets per liter of blood, [ 1] but investigation is typically only considered if the upper limit exceeds 750 × 10 9 /L. When the cause is unknown, the term ...
One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5] Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). [6] [7]
Frequency. 0.6-2.5/100,000 cases per year. [ 2] In hematology, essential thrombocythemia ( ET) is a rare chronic blood cancer ( myeloproliferative neoplasm) characterised by the overproduction of platelets (thrombocytes) by megakaryocytes in the bone marrow. [ 3] It may, albeit rarely, develop into acute myeloid leukemia or myelofibrosis. [ 3]
Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet ...
Platelet transfusion. Platelet transfusion, also known as platelet concentrate, is used to prevent or treat bleeding in people with either a low platelet count or poor platelet function. [ 1] Often this occurs in people receiving cancer chemotherapy. [ 1] Preventive transfusion is often done in those with platelet levels of less than 10 x 10 9 ...
In a typical set of rules, a platelet donor must weigh at least 50 kg (110 lb) and have a platelet count of at least 150 x 10 9 /L (150,000 platelets per mm³). [2] One unit has greater than 3×10 11 platelets. Therefore, it takes 2 liters of blood having a platelet count of 150,000/mm³ to produce one unit of platelets.
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