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  2. Etranacogene dezaparvovec - Wikipedia

    en.wikipedia.org/wiki/Etranacogene_dezaparvovec

    KEGG. D12500. Etranacogene dezaparvovec, sold under the brand name Hemgenix is a gene therapy used for the treatment of hemophilia B. [ 5 ][ 6 ][ 7 ] Etranacogene dezaparvovec is an adeno-associated virus vector-based gene therapy which consists of a viral vector carrying a gene for clotting Factor IX. [ 7 ] The gene is expressed in the liver ...

  3. Haemophilia - Wikipedia

    en.wikipedia.org/wiki/Haemophilia

    Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) 'blood' and φιλία (philía) 'love of'), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. [2][3] This results in people bleeding for a longer time after ...

  4. Haemophilia in European royalty - Wikipedia

    en.wikipedia.org/wiki/Haemophilia_in_European...

    Haemophilia figured prominently in the history of European royalty in the 19th and 20th centuries. Queen Victoria and her husband, Prince Albert, of the United Kingdom, through two of their five daughters – Princess Alice and Princess Beatrice – passed the mutation to various royal houses across the continent, including the royal families ...

  5. FDA Approves Pfizer's Second Hemophilia Drug With Six Months

    www.aol.com/fda-approves-pfizers-second...

    Hemophilia is a family of rare genetic blood diseases caused by a clotting factor deficiency (FVIII in hemophilia A, FIX in hemophilia B), impacting more than 800,000 people globally.

  6. A hemophilia drug that just won FDA approval pegs a one-time ...

    www.aol.com/news/hemophilia-drug-just-won-fda...

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  7. With Hemlibra, Roche seeks to break into tight hemophilia circle

    www.aol.com/news/hemlibra-roche-seeks-break...

    Swiss drugmaker Roche (ROG.S) is breaking into hemophilia A treatment, a $10 billion global market dominated by rivals who have cultivated close ties to sufferers of the genetic bleeding disorder.

  8. Acquired haemophilia - Wikipedia

    en.wikipedia.org/wiki/Acquired_haemophilia

    Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII. These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding ...

  9. Contaminated haemophilia blood products - Wikipedia

    en.wikipedia.org/wiki/Contaminated_haemophilia...

    Contaminated haemophilia blood products. Contaminated hemophilia blood products were a serious public health problem in the late 1970s up to 1985. Hemophilia A causes a deficiency in Factor VIII, a protein required for blood clotting. Factor VIII injections are a common treatment to prevent or stop bleeding in people with hemophilia A. [1]

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