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Peeling skin syndrome 1. Peeling skin syndrome 1 is caused by a genetic defect in the corneodesmosin (CDSN) gene. This gene localizes to the human epidermis and other epithelia. The protein experiences a chain of cleavages during corneocyte maturation. [6] Its symptoms include short stature, abnormality of metabolism/homeostasis, scaling skin ...
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]
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Psoriasis. Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [ 4][ 5] These areas are red, pink, or purple, dry, itchy, and scaly. [ 8][ 3] Psoriasis varies in severity from small localized patches to complete body coverage. [ 3] Injury to the skin can trigger psoriatic skin changes at that ...
Ichthyosis (also named fish scale disease) [ 1] is a family of genetic skin disorders characterized by dry, thickened, scaly skin. [ 2] The more than 20 types of ichthyosis range in severity of symptoms, outward appearance, underlying genetic cause and mode of inheritance (e.g., dominant, recessive, autosomal or X-linked ). [ 3]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
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Chemical peel. A chemical peel is a treatment used to improve and smooth the texture of the skin. The skin on the face is most commonly treated, but peels can also be performed on the body. Chemical peels are intended to remove the outermost layers of the skin. To accomplish this task, the chosen peel solution induces a controlled injury to the ...