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53027-39-7. ChemSpider. none. Neutral Protamine Hagedorn (NPH) insulin, also known as isophane insulin, is an intermediate-acting insulin given to help control blood sugar levels in people with diabetes. [ 3] It is used by injection under the skin once to twice a day. [ 1] Onset of effects is typically in 90 minutes and they last for 24 hours. [ 3]
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [ 13][ 14] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin. 1921 Research on the role of pancreas in ...
Insulin degludec is a modified insulin that has one single amino acid deleted in comparison to human insulin, and is conjugated to hexadecanedioic acid via gamma- L -glutamyl spacer at the amino acid lysine at position B29. It is included on the World Health Organization's List of Essential Medicines [ 11] as an equivalent to insulin glargine.
NPH insulin rather than insulin glargine is generally preferred in pregnancy. [8] After injection, microcrystals slowly release insulin for about 24 hours. [7] This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. [7] Insulin glargine was approved for medical use in the United States in ...
Hans Christian Hagedorn (1888-1971) Hans Christian Hagedorn (6 March 1888 – 6 October 1971) was the creator of NPH insulin and the founder of Nordisk Insulinlaboratorium, which is known today as Novo Nordisk .
1Y17CTI5SR. Regular insulin, also known as neutral insulin and soluble insulin, is a type of short-acting medical insulin. [2] It is used to treat type 1 diabetes, type 2 diabetes, gestational diabetes, and complications of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic states. [5] It is also used along with glucose to ...
Insulin detemir was approved for medical use in the European Union in June 2004, and in the United States in June 2005. [5] [6] [8] It is on the World Health Organization's List of Essential Medicines. [9] In 2021, it was the 117th most commonly prescribed medication in the United States, with more than 5 million prescriptions. [10] [11]
Insulin is a peptide hormone containing two chains cross-linked by disulfide bridges. Insulin (/ ˈ ɪ n. sj ʊ. l ɪ n /, [5] [6] from Latin insula, 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (INS) gene. It is the main anabolic hormone of the body. [7]
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