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The Better Business Bureau (BBB) is an American private, 501(c)(6) nonprofit organization founded in 1912. BBB's self-described mission is to focus on advancing marketplace trust, [2] consisting of 92 independently incorporated local BBB organizations in the United States and Canada, coordinated under the International Association of Better Business Bureaus (IABBB) in Arlington, Virginia.
A BBB-accredited company agrees to abide by a set of accreditation standards BBB says are "attributes of a better business." These include honesty in advertising, transparency, and responsiveness ...
The credit rating is a financial indicator to potential investors of debt securities such as bonds. These are assigned by credit rating agencies such as Moody's, Standard & Poor's, and Fitch, which publish code designations (such as AAA, B, CC) to express their assessment of the risk quality of a bond. Moody's assigns bond credit ratings of Aaa ...
Some reports point to the metalloproteinase-2 and interleukin-6 as culprits responsible for the BBB failure. [22] There is broad consensus that AQP4/NMO-IgG initially enters the brain via BBB-deficient sites such as the area postrema, where there is access to cerebrospinal fluid (CSF). [23] In any case, anti-AQP4 is produced mainly ...
The blood–brain barrier ( BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [ 1] The blood–brain barrier is formed by endothelial ...
Investigations. The following investigations are used in clearance determinations: [ 12] ANACI (Access National Agency Check with Inquiries) – Initial Confidential, Secret, L, LX; only used for civilian employees. NACLC (National Agency Check with Law and Credit) – Initial Confidential, Secret, L, LX; reinvestigations.
BBB National Programs, an independent non-profit organization that oversees more than a dozen national industry self-regulation programs that provide third-party accountability and dispute resolution services to companies, including outside and in-house counsel, consumers, and others in arenas such as privacy, advertising, data collection, child-directed marketing, and more.
Free Gd 3+ has a median lethal dose of 0.34 mmol/kg (IV, mouse) [17] or 100–200 mg/kg, but the LD50 is increased by a factor of 31 times [18] when Gd 3+ is chelated. [19] The spectrum of adverse drug reactions is greater with gadolinium-based contrast agents than with iodinated contrast agents (radiocontrast agents). [20]