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  2. What Is Scleroderma? Symptoms & Causes| NIAMS

    www.niams.nih.gov/health-topics/scleroderma

    Overview of Scleroderma. Scleroderma is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma. Too much collagen in your skin and ...

  3. Scleroderma Basics: Overview, Symptoms, and Causes

    www.niams.nih.gov/health-topics/scleroderma/basics/symptoms-causes

    Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. This inflammation leads to areas of tight, hard skin. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic ...

  4. Scleroderma: Diagnosis, Treatment, and Steps to Take

    www.niams.nih.gov/health-topics/scleroderma/diagnosis-treatment-and-steps-to-take

    Treatment of Scleroderma. Your treatment depends on the type of scleroderma you have, your symptoms, and which tissues and organs are affected. Treatment can help control the symptoms and limit damage. Your doctor may recommend medications, including: Anti-inflammatory medications to manage pain and reduce swelling.

  5. Scleroderma Basics: Diagnosis, Treatment, and Steps to Take

    www.niams.nih.gov/health-topics/scleroderma/basics/diagnosis-treatment-and...

    Living with the disease may be hard. To help, try to take an active part in treating your scleroderma. The following tips and suggestions may help. Keep warm. Dress in layers, wear gloves and socks, and avoid cold rooms and weather when possible. Try to avoid cold or wet environments that may trigger symptoms. If you smoke, quit.

  6. Scleroderma: Research & Resources - National Institute of...

    www.niams.nih.gov/health-topics/scleroderma/more-info

    Understanding why scleroderma can affect African Americans more severely. Evaluating how immunosuppressant and other medications can be used to help manage the symptoms and complications of scleroderma, particularly pulmonary complications. Exploring the many factors that lead to fibrosis to see if their development can be blocked.

  7. Scleroderma Genomics and Health Disparities Unit | NIAMS

    www.niams.nih.gov/labs/scleroderma-genomics-and-health-disparities-lab

    Scleroderma. Locations of the 25 GRASP consortium centers. Scleroderma (systemic sclerosis) is a chronic, multi-system, autoimmune disease characterized by progressive fibrosis of the skin and internal organs. There is a health disparity in African Americans, who have an increased prevalence of scleroderma compared to European Americans.

  8. Scleroderma, Fibrosis, and Autoinflammatory Disease Program

    www.niams.nih.gov/grants-funding/supported-scientific-areas/scleroderma...

    This program supports basic, translational, observational, and clinical studies on scleroderma, fibrosis, and autoinflammatory diseases. Scleroderma is an autoimmune rheumatic disease without an available curative therapy. It is a heterogenous and complex disease that can be categorized as localized scleroderma (morphea) and systemic scleroderma.

  9. Esclerodermia | Temas de salud | NIAMS

    www.niams.nih.gov/es/informacion-de-salud/esclerodermia

    Esclerodermia localizada, que solo afecta la piel y las estructuras directamente debajo de la piel. Esclerodermia sistémica, también llamada esclerosis sistémica, que afecta muchas partes del cuerpo. Este es el tipo más grave de esclerodermia y puede dañar los vasos sanguíneos y los órganos internos, como el corazón, los pulmones y los ...

  10. Esclerodermia | Temas de salud | NIAMS

    www.niams.nih.gov/es/informacion-de-salud/esclerodermia/diagnosis-treatment...

    Scleroderma can make your mouth dry and damage connective tissues in your mouth, speeding up tooth decay and causing your teeth to become loose. Tightening facial skin can also make your mouth opening smaller and narrower, which makes it harder to care for your teeth. Here are some ways to avoid tooth and gum problems:

  11. Esclerodermia | Temas de salud | NIAMS

    www.niams.nih.gov/es/informacion-de-salud/esclerodermia/more-info

    Esclerodermia. Research is finding better ways to treat symptoms, prevent organ damage and improve the quality of life for people with scleroderma. Multidisciplinary research has also provided new clues for understanding the disease, which is an important step toward prevention and cure. Studies of the immune system, genetics, cell biology and ...