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Hyperhomocysteinemia. Hyperhomocysteinemia is a medical condition characterized by an abnormally high level of total homocysteine (that is, including homocystine and homocysteine-cysteine disulfide) in the blood, conventionally described as above 15 μmol/L. [1] As a consequence of the biochemical reactions in which homocysteine is involved ...
Homocysteine (/ ˌhoʊmoʊˈsɪstiːn /) or Hcy: is a non-proteinogenic α-amino acid. It is a homologue of the amino acid cysteine, differing by an additional methylene bridge (-CH 2 -). It is biosynthesized from methionine by the removal of its terminal C ε methyl group.
[12] [43] The beneficial result may be associated with lowering circulating homocysteine concentration, as stratified analysis showed that risk was reduced more when there was a larger decrease in homocysteine. [12] [43] The effect was also larger for the studies that were conducted in countries that did not have mandatory grain folic acid ...
B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. [1][2] They are a chemically diverse class of compounds. [1] Dietary supplements containing all eight are referred to as a vitamin B complex. Individual B vitamins are referred to by B-number or by chemical name, such ...
LabCorp v. Metabolite, Inc., 548 U.S. 124 (2006), is the first case since Diamond v. Chakrabarty [1] in which the U.S. Supreme Court indicated a renewed interest in examining the limits of patentable subject matter for advances in life sciences. Although the Court initially agreed to hear the case, it was later dismissed in 2006 with three ...
High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. [1] Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. They are typically composed of 80–100 proteins per particle (organized by one, two or three ApoA).
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is S- (5-deoxy-D-ribos-5-yl)-L-homocysteine L-homocysteine-lyase [ (4S)-4,5-dihydroxypentan-2,3-dione-forming]. Other names in common use include S-ribosylhomocysteinase, and LuxS.
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