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Fluorescence biomodulation is a form of photobiomodulation, which utilizes fluorescence energy to induce multiple transduction pathways that can modulate biological processes through the activation of photoacceptors found within many different cell and tissue types. According to Magalhães and Yoshimura, photoacceptors are molecules that do not ...
Light Emitting Diode Therapy (LEDT) encompasses two primary therapeutic approaches: photodynamic Therapy (PDT) and photobiomodulation Therapy (PBMT). Photodynamic therapy (PDT) utilises light-sensitive compounds combined with LED light to generate reactive oxygen species, which selectively target and destroy abnormal cells.
The other major photostimulation method is the use of light to activate a light-sensitive protein such as rhodopsin, which can then excite the cell expressing the opsin. Scientists have long postulated the need to control one type of cell while leaving those surrounding it untouched and unstimulated.
The transcranial photobiomodulation or transcranial low level light therapy is limited in neuromodulation due to several reasons: An excessive dose of radiation can be harmful. [ 22 ] Therefore, at adequate doses of light there may be stimulation of growth, but at high doses excessive singlet oxygen may be produced and its chemical action may ...
Photobiology is the scientific study of the beneficial and harmful interactions of light (technically, non-ionizing radiation) in living organisms. [1] The field includes the study of photophysics, photochemistry, photosynthesis, photomorphogenesis, visual processing, circadian rhythms, photomovement, bioluminescence, and ultraviolet radiation effects.
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Optical scattering occurs due to mismatches in refractive index of the different tissue components, ranging from cell membranes to whole cells. Cell nuclei and mitochondria are the most important scatterers. [11] Their dimensions range from 100 nm to 6 μm, and thus fall within the NIR window.
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