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Lampbrush chromosome. Lampbrush chromosome are a special form of chromosome found in the growing oocytes (immature eggs) of most animals, except mammals. They were first described by Walther Flemming and Ruckert in 1882. [1] Lampbrush chromosomes of tailed and tailless amphibians, birds and insects are described best of all.
These chromosomes consist of more than 1000 copies of the same chromatid that are aligned and produce alternating dark and light bands when stained. The dark bands are the chromomere. It is unknown when chromomeres first appear on the chromosome. Chromomeres can be observed best when chromosomes are highly condensed. [2]
Chromosomes display a banded pattern when treated with some stains. Bands are alternating light and dark stripes that appear along the lengths of chromosomes. Unique banding patterns are used to identify chromosomes and to diagnose chromosomal aberrations, including chromosome breakage, loss, duplication, translocation or inverted segments.
The ability for mammals to tolerate aneuploidies in the sex chromosomes arises from the ability to inactivate them, which is required in normal females to compensate for having two copies of the chromosome. Not all genes on the X chromosome are inactivated, which is why there is a phenotypic effect seen in individuals with extra X chromosomes.
This is an accepted version of this page This is the latest accepted revision, reviewed on 23 January 2025. DNA molecule containing genetic material of a cell This article is about the DNA molecule. For the genetic algorithm, see Chromosome (genetic algorithm). Chromosome (10 7 - 10 10 bp) DNA Gene (10 3 - 10 6 bp) Function A chromosome and its packaged long strand of DNA unraveled. The DNA's ...
Lampbrush chromosome from the cell nucleus of an ovarial egg from Triton sp., a salamander. Harold Garnet Callan FRS FRSE (15 March 1917, in Maidenhead – 3 November 1993), [1] known as Mick Callan, was an English zoologist and cytologist. [2] He is especially remembered for his work on Lampbrush chromosomes.
These supernumerary chromosomes are commonly observed in angiosperms, specifically the flowering plants bred through outcrossing. [ 7 ] The obscure development of B-chromosomes is supported by the irregularity of their appearances in specific species populations.
Endoreduplication is commonly observed in cells responsible for the nourishment and protection of oocytes and embryos. It has been suggested that increased gene copy number might allow for the mass production of proteins required to meet the metabolic demands of embryogenesis and early development. [ 1 ]