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Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). [5] It is used in the treatment of various conditions, most notably obsessive–compulsive disorder but also many other disorders, including hyperacusis, panic disorder, major depressive disorder, trichotillomania, [6] body dysmorphic disorder [7] [8] [9] and chronic pain. [5]
Clomipramine. Doxepin. Imipramine. Older antidepressant medications like tricyclic antidepressants typically have a higher risk of side effects than the more modern SSRI and SNRI medications ...
Side effects may also be less troublesome if treatment is initiated with low doses and then gradually increased, although this may also delay the beneficial effects. TCAs can behave like class 1A antiarrhythmics , as such, they can theoretically terminate ventricular fibrillation, decrease cardiac contractility and increase collateral blood ...
Anafranil (clomipramine) – a tricyclic antidepressant; mostly used to treat OCD Antabuse ( disulfiram ) – inhibits the enzyme acetaldehyde dehydrogenase , causing acetaldehyde poisoning when ethanol is consumed; used to cause severe hangover when drinking; increases liver, kidney, and brain damage from drinking
Effects of chloro, methoxy and trifluoromethyl substituents in the aromatic ring of cycloalkanol ethylamine scaffold were tested. The results showed that the strongest electron-withdrawing m -trifluoromethyl analogue exhibited the most potent inhibitory effect of norepinephrine and the most selectivity over serotonin uptake. [ 36 ]
Tragic death of a 34-year-old Disney influencer raises the alarm about dangers of living with food allergies. Beth Greenfield. Updated December 9, 2024 at 2:52 PM.
These side effects can be contributed to the multiple receptors that imipramine targets such as serotonin, norepinephrine, dopamine, acetylcholine, epinephrine, histamine. Those listed in italics below denote common side effects, separated by the organ systems that are affected. [ 20 ]
An explosion at a chemical facility in Louisville, Kentucky Tuesday afternoon left at least 11 people hospitalized, officials confirmed.. The blast occurred around 3 p.m. local time at the ...