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Cocaine stimulates the mesolimbic pathway in the brain. [15] Mental effects may include an intense feeling of happiness, sexual arousal, loss of contact with reality, or agitation. [12] Physical effects may include a fast heart rate, sweating, and dilated pupils. [12] High doses can result in high blood pressure or high body temperature. [16]
Niemann isolated cocaine from coca leaves in 1859. In the 19th century, there was great interest among European chemists in the effects of coca leaves discovered in Latin America . In 1855 the chemist Friedrich Gaedcke had published a treatise on an active alkaloid extract of the coca leaf he called erythroxyline , after the genus Erythroxylum ...
By the 17th century, when those buried in the crypt would have lived, Milan (then a possession of Spain) was a major importer of exotic plants, especially from the Americas, so cocaine could’ve ...
In 1858 Dr. M. Sales Giron invented the first pressurized inhaler. Amphetamine was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanu who named it phenylisopropylamine ; [ 23 ] [ 24 ] [ 25 ] its stimulant effects remained unknown until 1927, when it was independently resynthesized by Gordon Alles and reported to have ...
Coca leaf is the raw material for the manufacture of the drug cocaine, a powerful stimulant and anaesthetic extracted chemically from large quantities of coca leaves. Today, since it has mostly been replaced as a medical anaesthetic by synthetic analogues such as procaine, cocaine is best known as an illegal recreational drug.
Cocaine was later removed in 1903 and substituted with caffeine as the primary stimulant. *You may be allergic to Coke and not know it because they are not obligated by law to reveal its "secret ...
Chemical structure of cocaine. The biosynthesis of cocaine has long attracted the attention of biochemists and organic chemists. This interest is partly motivated by the strong physiological effects of cocaine, but a further incentive was the unusual bicyclic structure of the molecule. The biosynthesis can be viewed as occurring in two phases ...
Coca-Cola included caffeine in its original recipe (alongside trace amounts of cocaine). Caffeine is everywhere, but one particular niche in the beverage market gets an especially bad rap—energy ...