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  2. Minimal important difference - Wikipedia

    en.wikipedia.org/wiki/Minimal_important_difference

    The minimal important difference (MID) or minimal clinically important difference (MCID) is the smallest change in a treatment outcome that an individual patient would identify as important and which would indicate a change in the patient's management.

  3. Clinical significance - Wikipedia

    en.wikipedia.org/wiki/Clinical_significance

    In broad usage, the "practical clinical significance" answers the question, how effective is the intervention or treatment, or how much change does the treatment cause. In terms of testing clinical treatments, practical significance optimally yields quantified information about the importance of a finding, using metrics such as effect size, number needed to treat (NNT), and preventive fraction ...

  4. Signs and symptoms - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms

    A medical sign is an objective observable indication of a disease, injury, or medical condition that may be detected during a physical examination. [7] These signs may be visible, such as a rash or bruise, or otherwise detectable such as by using a stethoscope or taking blood pressure.

  5. Surrogate endpoint - Wikipedia

    en.wikipedia.org/wiki/Surrogate_endpoint

    A surrogate endpoint of a clinical trial is a laboratory measurement or a physical sign used as a substitute for a clinically meaningful endpoint that measures directly how a patient feels, functions or survives. Changes induced by a therapy on a surrogate endpoint are expected to reflect changes in a clinically meaningful endpoint. [8]

  6. Medical terminology - Wikipedia

    en.wikipedia.org/wiki/Medical_terminology

    Suffixes are attached to the end of a word root to add meaning such as condition, disease process, or procedure. In the process of creating medical terminology, certain rules of language apply. These rules are part of language mechanics called linguistics. The word root is developed to include a vowel sound following the term to add a smoothing ...

  7. Clinical endpoint - Wikipedia

    en.wikipedia.org/wiki/Clinical_endpoint

    Clinical endpoints or clinical outcomes are outcome measures referring to occurrence of disease, symptom, sign or laboratory abnormality constituting a target outcome in clinical research trials. The term may also refer to any disease or sign that strongly motivates withdrawal of an individual or entity from the trial, then often termed a ...

  8. Medical diagnosis - Wikipedia

    en.wikipedia.org/wiki/Medical_diagnosis

    Radiography is an important tool in diagnosis of certain disorders. Medical diagnosis (abbreviated Dx, [1] D x, or D s) is the process of determining which disease or condition explains a person's symptoms and signs. It is most often referred to as a diagnosis with the medical context being implicit.

  9. Phenotype (clinical medicine) - Wikipedia

    en.wikipedia.org/wiki/Phenotype_(clinical_medicine)

    For example, the term 'phenotype' in the field of chronic obstructive pulmonary disease (COPD) means "a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes", [3] but nearly all specialities use this meaning in some way, like in asthma research. [4]