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  2. Voclosporin - Wikipedia

    en.wikipedia.org/wiki/Voclosporin

    Lupus nephritis commonly leads patients to chronic kidney failure and therefore places an emphasis on early intervention for improving treatment outcomes. It is a significant risk factor for morbidity and mortality in systemic lupus erythematosus. The management of lupus nephritis comprises immunosuppressive therapy to lessen inflammation and ...

  3. Belimumab - Wikipedia

    en.wikipedia.org/wiki/Belimumab

    Belimumab is primarily used in people with systemic lupus erythematosus. When it was introduced in 2011, it was the first new drug approved to treat lupus in 56 years. [8] Sales rose to $31.2 million in the first quarter of 2012. [37] The total cost for the first year of treatment with belimumab is $28,000. [38]

  4. Lupus nephritis - Wikipedia

    en.wikipedia.org/wiki/Lupus_nephritis

    Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases.

  5. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Certain types of lupus nephritis such as diffuse proliferative glomerulonephritis require intermittent cytotoxic drugs. These drugs include cyclophosphamide and mycophenolate . Cyclophosphamide increases the risk of developing infections, pancreas problems, high blood sugar, and high blood pressure.

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    When used as drugs, the International Nonproprietary Names ... systemic lupus erythematosus, lupus nephritis, acute graft-versus-host disease: Olokizumab [75] mab:

  7. Mizoribine - Wikipedia

    en.wikipedia.org/wiki/Mizoribine

    Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation, and in steroid-resistant nephrotic syndrome, IgA nephropathy, lupus, as well as for adults with rheumatoid arthritis, lupus nephritis and other rheumatic diseases.

  8. Mycophenolic acid - Wikipedia

    en.wikipedia.org/wiki/Mycophenolic_acid

    Mycophenolic acid is an immunosuppressant medication used to prevent rejection following organ transplantation and to treat autoimmune conditions such as Crohn's disease and lupus. [ 13 ] [ 14 ] Specifically it is used following kidney , heart , and liver transplantation . [ 14 ]

  9. Cyclophosphamide - Wikipedia

    en.wikipedia.org/wiki/Cyclophosphamide

    For example, systemic lupus erythematosus with severe lupus nephritis may respond to pulsed cyclophosphamide. Cyclophosphamide is also used to treat minimal change disease, [8] severe rheumatoid arthritis, granulomatosis with polyangiitis, [5] Goodpasture syndrome [9] and multiple sclerosis. [10]

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