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  2. Acid-growth hypothesis - Wikipedia

    en.wikipedia.org/wiki/Acid-growth_hypothesis

    The acid-growth hypothesis is a theory that explains the expansion dynamics of cells and organs in plants. It was originally proposed by Achim Hager and Robert Cleland in 1971. [1] [2] They hypothesized that the naturally occurring plant hormone, auxin (indole-3-acetic acid, IAA), induces H + proton extrusion into the apoplast.

  3. Plant sources of anti-cancer agents - Wikipedia

    en.wikipedia.org/wiki/Plant_sources_of_anti...

    Extracts from Camptotheca (the "happy tree" or "cancer tree") were used to develop the chemotherapeutic drug Topotecan. Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans. [1] [2]

  4. Denaturation (biochemistry) - Wikipedia

    en.wikipedia.org/wiki/Denaturation_(biochemistry)

    In biochemistry, denaturation is a process in which proteins or nucleic acids lose folded structure present in their native state due to various factors, including application of some external stress or compound, such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), agitation and radiation, or heat. [3]

  5. Hyperchromicity - Wikipedia

    en.wikipedia.org/wiki/Hyperchromicity

    The most famous example is the hyperchromicity of DNA that occurs when the DNA duplex is denatured. [1] The UV absorption is increased when the two single DNA strands are being separated, either by heat or by addition of denaturant or by increasing the pH level. The opposite, a decrease of absorbance is called hypochromicity.

  6. Denaturation - Wikipedia

    en.wikipedia.org/wiki/Denaturation

    Denaturation (biochemistry), a structural change in macromolecules caused by extreme conditions; Denaturation (fissile materials), transforming fissile materials so that they cannot be used in nuclear weapons; Denaturation (food), intentional adulteration of food or drink rendering it unfit for consumption while remaining suitable for other uses

  7. DNA repair - Wikipedia

    en.wikipedia.org/wiki/DNA_repair

    Wikipedia articles on each of the genes highlighted by red, gray or cyan describe the epigenetic alteration(s) and the cancer(s) in which these epimutations are found. Review articles, [ 116 ] and broad experimental survey articles [ 117 ] [ 118 ] also document most of these epigenetic DNA repair deficiencies in cancers.

  8. Apoptosis - Wikipedia

    en.wikipedia.org/wiki/Apoptosis

    Defects in regulation of apoptosis in cancer cells occur often at the level of control of transcription factors. As a particular example, defects in molecules that control transcription factor NF-κB in cancer change the mode of transcriptional regulation and the response to apoptotic signals, to curtail dependence on the tissue that the cell ...

  9. History of biochemistry - Wikipedia

    en.wikipedia.org/wiki/History_of_biochemistry

    Some argued that the beginning of biochemistry may have been the discovery of the first enzyme, diastase (today called amylase), in 1833 by Anselme Payen, [2] while others considered Eduard Buchner's first demonstration of a complex biochemical process alcoholic fermentation in cell-free extracts to be the birth of biochemistry.