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The respiratory system is the most common system to be affected and the complications are the leading cause of death in SMA types 0/1 and 2. SMA type 3 can have similar respiratory problems, but it is more rare. [24] Complications arise due to weakened intercostal muscles because of the lack of stimulation from the nerve.
The Singapore Medical Association (abbreviated SMA) is a professional association representing the interests of medical professionals in Singapore. It was established on September 15, 1959, replacing the Malaya Branch of the British Medical Association. [2] As of 2020, it had over 8,200 members. [3]
Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.
10q22.1: Autosomal recessive: Prenatal onset, characterised by severe muscle wasting, respiratory and feeding failure, and bone fractures at birth as in arthrogryposis multiplex congenita, usually fatal in infancy [2] [3] [4] PCH: Spinal muscular atrophy with pontocerebellar hypoplasia (SMA-PCH) Pontocerebellar hypoplasia type 1A (PCH1A) 607596 ...
Singapore's health ministry on Wednesday confirmed another 1,016 cases of the novel coronavirus, taking the total infections in the Southeast Asian island nation to 10,141. It also reported its ...
Cause of death % of total deaths 1: Cancer: 29.1 2: Pneumonia: 20.1 3: Ischaemic heart diseases: 18.5 4: Cerebrovascular disease (including stroke) 6.3 5: External causes of morbidity and mortality: 4.0 6: Hypertensive diseases (including hypertensive heart disease) 3.4 7: Nephritis, nephrotic syndrome and nephrosis: 2.4 8: Urinary tract ...
The Singapore Medical Journal is a monthly peer-reviewed general medical journal. It was established in 1960 and is published by Medknow Publications on behalf of the Singapore Medical Association. The editor-in-chief is Poh Kian Keong. According to the Journal Citation Reports, the journal has a 2021 impact factor of 3.331. [1]
Singapore, the city state of 5.7 million people has seemingly weathered the COVID-19 storm better than anywhere else in the world, with a death rate of only 0.05% - way lower than the global ...