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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
This may lead to nosebleeds or bleeding gums, especially after brushing the teeth. There may also be many tiny red spots or bruises that appear on the arms or legs (known as petechia). Tiredness and weakness (fatigue) during and after treatment – most people find their energy levels are back to normal within 6 months to a year.
Chemotherapy-induced peripheral neuropathy is a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs caused by some chemotherapy agents.
What it looks like: Fifth Disease is caused by Parvovirus B19 and presents with a red rash on the cheeks, arms, and legs that can last for several weeks. This condition occurs most often in children.
Paclitaxel and oxaliplatin, representatives from two of the six major antineoplastic agents causing CIPN, cause acute neuropathy, which manifests during or immediately after treatment infusion. [1] The other four groups of agents generally cause late symptoms that emerge weeks after the completion of chemotherapy.
Pastia's sign, Pastia lines, or Thompson's sign is a clinical sign in which pink or red lines formed of confluent petechiae are found in skin creases, particularly the crease in the antecubital fossa, the soft depression on the inside of the arm; the folding crease divides this fossa where the forearm meets the (upper) arm (the biceps, triceps, humerus section of the upper extremity); the ...
Neuropathy: Chemotherapy-induced peripheral neuropathy, a progressive and enduring tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs.
Radiation dermatitis (also known as radiodermatitis) is a skin disease associated with prolonged exposure to ionizing radiation. [3]: 131–2 Radiation dermatitis occurs to some degree in most patients receiving radiation therapy, with or without chemotherapy.