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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Cherry angioma, also called cherry hemangioma [1] or Campbell de Morgan Spot, [2] is a small bright red dome-shaped bump on the skin. [3] It ranges between 0.5 – 6 mm in diameter and usually several are present, typically on the chest and arms, and increasing in number with age. [3] [4] If scratched, they may bleed. [5]
Chemotherapy-induced peripheral neuropathy is a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs caused by some chemotherapy agents.
Purpura (/ ˈ p ɜːr p jʊər ə / [1]) is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure. The spots are caused by bleeding underneath the skin secondary to platelet disorders, vascular disorders, coagulation disorders, or other causes. [2]
What it looks like: Fifth Disease is caused by Parvovirus B19 and presents with a red rash on the cheeks, arms, and legs that can last for several weeks. This condition occurs most often in children.
This may lead to nosebleeds or bleeding gums, especially after brushing the teeth. There may also be many tiny red spots or bruises that appear on the arms or legs (known as petechia). Tiredness and weakness (fatigue) during and after treatment – most people find their energy levels are back to normal within 6 months to a year.
If a patient experiences such abnormalities in sensation, then CIPN should be suspected. Furthermore, most CIPN symptoms appear during the first two months of treatment, progress during treatment, and stabilize after completion. It would be unexpected for CIPN to first appear weeks or months after the last dose of chemotherapy treatment. [1]
Erythema (Ancient Greek: ἐρύθημα, from Greek erythros 'red') is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. [1] It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology include nervous blushes. [2]