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The host-pathogen interaction is defined as how microbes or viruses sustain themselves within host organisms on a molecular, cellular, organismal or population level. This term is most commonly used to refer to disease-causing microorganisms although they may not cause illness in all hosts. [ 1 ]
Mathematical models need to integrate the increasing volume of data being generated on host-pathogen interactions. Many theoretical studies of the population dynamics , structure and evolution of infectious diseases of plants and animals, including humans, are concerned with this problem.
The Pathogen-Host Interactions database (PHI-base) [1] is a biological database that contains manually curated information on genes experimentally proven to affect the outcome of pathogen-host interactions. The database has been maintained by researchers at Rothamsted Research and external collaborators since 2005.
For the full specification of the model, the arrows should be labeled with the transition rates between compartments. Between S and I, the transition rate is assumed to be (/) / = /, where is the total population, is the average number of contacts per person per time, multiplied by the probability of disease transmission in a contact between a susceptible and an infectious subject, and / is ...
A diagram showing the infecting structures and effector delivery strategies of a model hemibiotrophic pathogen, Phytophthora infestans. Fungal effectors are proteins or non-proteinaceous molecules (such as RNAs or small molecules) secreted by pathogenic fungi into a host organism in order to modulate the host's immune response. [1] [2] [3]
Disease ecology is a sub-discipline of ecology concerned with the mechanisms, patterns, and effects of host-pathogen interactions, particularly those of infectious diseases. [1] For example, it examines how parasites spread through and influence wildlife populations and communities.
Robert Hermann Koch (11 December 1843 – 27 May 1910) was a German physician who developed Koch's postulates. [1]Koch's postulates (/ k ɒ x / KOKH) [2] are four criteria designed to establish a causal relationship between a microbe and a disease.
In epidemiology, particularly in the discussion of infectious disease dynamics (modeling), the latent period (also known as the latency period or the pre-infectious period) is the time interval between when an individual or host is infected by a pathogen and when that individual becomes infectious, i.e. capable of transmitting pathogens to ...