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  2. Promethazine - Wikipedia

    en.wikipedia.org/wiki/Promethazine

    Promethazine has a variety of medical uses, including: Sedation [13] In Germany, it is approved for the treatment of agitation and agitation associated with underlying psychiatric disorders with a maximum daily dose of 200 mg. [14] For nausea and vomiting associated with anesthesia or chemotherapy. It is commonly used postoperatively as an ...

  3. Lean (drug) - Wikipedia

    en.wikipedia.org/wiki/Lean_(drug)

    Ingredients for creating lean, including codeine-promethazine cough syrup, Jolly Rancher candies, and Sprite. Note the label on the bottled syrup, printed with instructions on how to prepare the lean. Some of the syrup has been decanted into a plastic container. A spoonful of promethazine/ codeine syrup showing the characteristic purple color

  4. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...

  5. Codeine - Wikipedia

    en.wikipedia.org/wiki/Codeine

    Codeine is also available in conjunction with the anti-nausea medication promethazine in the form of a syrup. Brand named as Phenergan with Codeine or in generic form as promethazine with Codeine, it began to be mixed with soft drinks in the 1990s as a recreational drug, called 'syrup', 'lean', or ' purple drank '. [ 63 ]

  6. Acepromazine - Wikipedia

    en.wikipedia.org/wiki/Acepromazine

    Acepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, [4] but is now almost exclusively used on animals as a sedative and antiemetic.

  7. Recreational use of dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Recreational_use_of_dext...

    Due to dextromethorphan's selective serotonin reuptake inhibitor-like action, the sudden cessation of recreational dosing in tolerant individuals can result in mental and physical withdrawal symptoms similar to the withdrawal from SSRIs. These withdrawal effects can manifest as psychological effects, including depression, irritability, cravings ...

  8. Levomepromazine - Wikipedia

    en.wikipedia.org/wiki/Levomepromazine

    Levomepromazine, also known as methotrimeprazine, is a phenothiazine neuroleptic drug.Brand names include Nozinan, Levoprome, Detenler, Hirnamin, Levotomin and Neurocil. It is a low-potency antipsychotic (approximately half as potent as chlorpromazine) with strong analgesic, hypnotic and antiemetic properties that are primarily used in palliative care.

  9. Cold medicine - Wikipedia

    en.wikipedia.org/wiki/Cold_medicine

    Cold syrup overdose has been linked to visual and auditory hallucinations as well as rapid involuntary jaw, tongue, and eye movements in children. [ medical citation needed ] Decongestants are possibly harmful to people with high blood pressure or a heart disease because these substances can constrict the blood vessels.