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Similar failure processes are involved in brain failure following reversal of cardiac arrest; [3] control of these processes is the subject of ongoing research. Repeated bouts of ischemia and reperfusion injury also are thought to be a factor leading to the formation and failure to heal of chronic wounds such as pressure sores and diabetic foot ...
Closed head injury (coup contrecoup) can damage more than the impact sites on the brain, as axon bundles may be torn or twisted, blood vessels may rupture, and elevated intracranial pressure can distort the walls of the ventricles. [7] [10] [11] Diffuse axonal injury is a key pathology in concussive brain injury. [5] The visual system may be ...
The pathophysiology of obesity involves many possible pathophysiological mechanisms involved in its development and maintenance. [28] [29] This field of research had been almost unapproached until the leptin gene was discovered in 1994 by J. M. Friedman's laboratory. [30] These investigators postulated that leptin was a satiety factor.
Currently, the pathophysiological mechanisms which produce post-traumatic amnesia are not completely known. The most common research strategy to clarify these mechanisms is the examination of the impaired functional capabilities of people with post-traumatic amnesia (PTA) after a traumatic brain injury. [15]
Major trauma is a severe traumatic injury that has the potential to cause disability or death. Serious traumatic injury most often occurs as a result of traffic collisions. [11] Traumatic injury is the leading cause of death in people under the age of 45. [12] Blunt trauma injuries are caused by the forceful impact of an external object.
The dislocation of ulnar head in Galeazzi fracture dislocation may be dorsal (commoner) or volar (rare) depending on the mechanism of injury. If the fall is on the outstretched hand with forearm in pronation, the dislocation is dorsal, and if forearm is in supination at the time of injury, the dislocation is volar.
Injury is physiological damage to the living tissue of any organism, whether in humans, in other animals, or in plants. Injuries can be caused in many ways, including mechanically with penetration by sharp objects such as teeth or with blunt objects , by heat or cold, or by venoms and biotoxins .
Nerve compression is a result of poor posture, prolonged computer use is an example of repetitive strain injury which affects the musculoskeletal system. [ 16 ] [ 2 ] Whiplash injury , whereby the force causes strain to the capsule and ligaments of the apophyseal joints of the cervical spine . [ 7 ]