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Martin A. Samuels (June 24, 1945 – June 6, 2023) was an American physician, neurologist, and medical educator whose distinctive teaching style and contributions, which were accessible to a broad audience, were widely recognized and celebrated. [1]
The FitzHugh–Nagumo model is a simplication of the Hodgkin–Huxley model. The Hindmarsh–Rose model is an extension which describes neuronal spike bursts. The Morris–Lecar model is a modification which does not generate spikes, but describes slow-wave propagation, which is implicated in the inhibitory synaptic mechanisms of central ...
Attractor networks have largely been used in computational neuroscience to model neuronal processes such as associative memory [2] and motor behavior, as well as in biologically inspired methods of machine learning. An attractor network contains a set of n nodes, which can be represented as vectors in a d-dimensional space where n>d.
The model suggests consciousness as a "mental state embodied through TRN-modulated synchronization of thalamocortical networks". In this model the thalamic reticular nucleus (TRN) is suggested as ideally suited for controlling the entire cerebral network, and responsible (via GABAergic networking) for synchronization of neural activity.
A 'second wave' connectionist (ANN) model with a hidden layer. Connectionism is an approach to the study of human mental processes and cognition that utilizes mathematical models known as connectionist networks or artificial neural networks. [1] Connectionism has had many "waves" since its beginnings.
The response of whole neuron model i.e. soma and dendrites, can be written in closed form. The response of the spatially extended model to periodic forcing is described by stroboscopic map. A Arnol'd tongue quasi-active model can be constructed with a linear stability analysis of the map with carefully treating the non-differentiability of soma ...
[3] Martin A. Samuels, MD, elaborates further on still another process of death, stating that with the release of adrenaline and an increased heart rate, sometimes catecholamines, stress hormones, will build up, leading to calcium channels opening and remaining open, resulting in an overflow of calcium into the system, killing off cells. [4]
Learned helplessness is the behavior exhibited by a subject after enduring repeated aversive stimuli beyond their control. It was initially thought to be caused by the subject's acceptance of their powerlessness, by way of their discontinuing attempts to escape or avoid the aversive stimulus, even when such alternatives are unambiguously presented.