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2. Here's how Tylenol holds up against other common pain relievers

   www.aol.com/heres-tylenol-holds-against-other...

   The recommended dose of Tylenol for adults is 325 to 650 milligrams every four to six hours. You should not have more than 3,000 to 4,000 milligrams of Tylenol in a span of 24 hours, recommends Walia.

3. Nonsteroidal anti-inflammatory drug - Wikipedia

   en.wikipedia.org/wiki/Nonsteroidal_anti...

   COX-2 is an enzyme facultatively expressed in inflammation, and it is inhibition of COX-2 that produces the desirable effects of NSAIDs. [125] When nonselective COX-1/COX-2 inhibitors (such as aspirin, ibuprofen, and naproxen) lower stomach prostaglandin levels, ulcers of the stomach or duodenum and internal bleeding can result. [126]

4. Ibuprofen/paracetamol - Wikipedia

   en.wikipedia.org/wiki/Ibuprofen/paracetamol

   Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]

5. Ibuprofen - Wikipedia

   en.wikipedia.org/wiki/Ibuprofen

   Allowing sufficient time between doses of ibuprofen and immediate-release (IR) aspirin can avoid this problem. The recommended elapsed time between a dose of ibuprofen and a dose of aspirin depends on which is taken first. It would be 30 minutes or more for ibuprofen taken after IR aspirin, and 8 hours or more for ibuprofen taken before IR aspirin.

6. Paracetamol - Wikipedia

   en.wikipedia.org/wiki/Paracetamol

   Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Paracetamol relieves pain in both acute mild migraine and episodic tension headache.

7. Equianalgesic - Wikipedia

   en.wikipedia.org/wiki/Equianalgesic

   Acute use (1–3 days) yields a potency about 1.5× stronger than that of morphine and chronic use (7 days+) yields a potency about 2.5 to 5× that of morphine. Similarly, the effect of tramadol increases after consecutive dosing due to the accumulation of its active metabolite and an increase of the oral bioavailability in chronic use.