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Ethanol does not bind to plasma proteins or other biomolecules. [13] [2] [3] The rate of distribution depends on blood supply, [4] specifically the cross-sectional area of the local capillary bed and the blood flow per gram of tissue. [13] As such, ethanol rapidly affects the brain, liver, and kidneys, which have high blood flow. [2]
In humans, however, rhodanese is concentrated in the kidneys (0.96 units/mg protein) and liver (0.15 u/mg), with concentrations in lung, brain, muscle and stomach not exceeding 0.03 U/ml. [43] In all these tissues, it is found in the mitochondrial matrix, a site of low accessibility for ionized, inorganic species, such as thiosulfate. This ...
[4] [23] Lactulose does not appear to be more effective than lactitol for treating people with hepatic encephalopathy. [23] Side effects of lactulose and lactitol include the possibility of diarrhea, abdominal bloating, gassiness, and nausea. [23] In acute liver failure, it is unclear whether lactulose is beneficial.
W hen Katie Coleman was diagnosed at age 29 with a softball-sized tumor on her right kidney and a host of smaller growths in her liver, she was stunned. That astonishment quickly gave way to ...
Nonalcoholic fatty liver disease (NAFLD) is a silent condition that can affect anyone, regardless of age or lifestyle. According to the National Institute of Diabetes and Digestive and Kidney ...
First, methanol (whether it enters the body by ingestion, inhalation, or absorption through the skin) can be fatal due to its CNS depressant properties in the same manner as ethanol poisoning. Second, in a process of toxication , it is metabolized to formic acid (which is present as the formate ion) via formaldehyde in a process initiated by ...
"Fatty liver disease, particularly NAFLD, is emerging as a leading cause of chronic liver disease, cirrhosis and liver cancer, as well as an important risk factor for type 2 diabetes and ...
Common side effects include anxiety, headache, sleepiness, cough, and nausea. [5] Serious side effects may include kidney problems, liver problems, low blood pressure, and malignant hyperthermia. [5] [4] It is unclear if it is safe in either pregnancy or breastfeeding. [5]
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