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A systemic disease is one that affects a number of organs and tissues, or affects the body as a whole. [1] It differs from a localized disease , which is a disease affecting only part of the body (e.g., a mouth ulcer ).
A moderate but definite systemic disturbance, caused either by the condition that is to be treated or surgical intervention or which is caused by other existing pathological processes, forms this group. Examples: Mild diabetes. Functional capacity I or IIa. Psychotic patients unable to care for themselves. Mild acidosis. Anemia moderate.
Mild disease correlates with fewer than four stools daily; in addition, mild urgency and rectal bleeding may occur intermittently. [19] Mild disease lacks systemic signs of toxicity (e.g. fever, chills, weight changes) and exhibits normal levels of the serum inflammatory markers ESR and CRP. [23]
Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
Also called silent disease, silent stage, or asymptomatic disease. This is a stage in some diseases before the symptoms are first noted. [23] Terminal phase If a person will die soon from a disease, regardless of whether that disease typically causes death, then the stage between the earlier disease process and active dying is the terminal phase.
UCTD itself usually has a mild clinical course, particularly if there is low organ involvement. Most patients who remain undifferentiated tend to not experience major organ involvement. [23] Up to 10–20% of patients diagnosed with UCTD will never progress to a defined disease and their symptoms will decrease or disappear. [3]
By Doyinsola Oladipo. NEW YORK (Reuters) - U.S.-based travel companies, from Marriott International to Booking Holdings are trimming their budgets and workforce ahead of next year as falling ...
IgG4-related disease (IgG4-RD), formerly known as IgG4-related systemic disease, is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, various degrees of fibrosis (scarring) and a usually prompt response to oral steroids.