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  2. Dextran - Wikipedia

    en.wikipedia.org/wiki/Dextran

    Dextran chains are of varying lengths (from 3 to 2000 kilodaltons). The polymer main chain consists of α-1,6 glycosidic linkages between glucose monomers, with branches from α-1,3 linkages. This characteristic branching distinguishes a dextran from a dextrin, which is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages. [2]

  3. Acetalated dextran - Wikipedia

    en.wikipedia.org/wiki/Acetalated_dextran

    Acetalated dextran's degradation time can vary from hours to a month or more at pH 7.2. [4] [5] [6] Also, acetalated dextran is unique because it is acid sensitive. Therefore, at lower pH acetalated dextran degrades more rapidly, which results in a polymer that degrades approximately two logs faster at pH 5 compared to pH 7.

  4. Dextran drug delivery systems - Wikipedia

    en.wikipedia.org/wiki/Dextran_drug_delivery_systems

    Dextran prodrugs are chemically linked drug-polymer complexes in which enzymatic processes and hydrolysis in vivo cause the drug to become pharmacologically active. Therapeutic agents can be linked to dextran via an ester bond which can be hydrolyzed slowly by esterases to produce sustained, stable drug release.

  5. Dextran sulphate sodium - Wikipedia

    en.wikipedia.org/wiki/Dextran_sulphate_sodium

    Dextran sulphate sodium (DSS), or dextran sodium sulphate (or any of the former with "sulfate") is a synthetic sulphated polysaccharide with anticoagulant activity used in immunological research to induce colitis. [1] [2] Dextran polymer molecules with a molecular weight of 36–50 kDa are frequently used to this end. [2]

  6. Dextranomer - Wikipedia

    en.wikipedia.org/wiki/Dextranomer

    Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI). [5] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent.

  7. Sephadex - Wikipedia

    en.wikipedia.org/wiki/Sephadex

    Sephadex is a cross-linked dextran gel used for gel filtration. It was launched by Pharmacia in 1959, after development work by Jerker Porath and Per Flodin. [1] [2] The name is derived from separation Pharmacia dextran. It is normally manufactured in a bead form and most commonly used for gel filtration columns. By varying the degree of cross ...

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