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Although the methods of action are not yet completely understood, it is hypothesized that medication-associated osteonecrosis of the jaw is related to a defect in jaw bone healing and remodelling. The inhibition of osteoclast differentiation and function, precipitated by drug therapy, leads to decreased bone resorption and remodelling.
Adverse effects of this approach also include pain, nerve damage, and loss of sensation due to the location of the inferior alveolar nerve. Anti-inflammatory medication can be used to slow the resorption process. Arthrocentesis, and arthroscopic surgery are also sometimes used to treat disc displacement and other symptoms. [2]
The TMJs are sometimes described as one of the most used joints in the body. Over time, either with normal use or with parafunctional use of the joint, wear and degeneration can occur, termed osteoarthritis. Rheumatoid arthritis, an autoimmune joint disease, can also affect the TMJs. Degenerative joint diseases may lead to defects in the shape ...
Osteoarthritis (OA) is the most common form of arthritis. [62] It affects humans and other animals, notably dogs, but also occurs in cats and horses. It can affect both the larger (ie. knee, hip, shoulder, etc.) and the smaller joints (ie. fingers, toes, foot, etc.) of the body. The disease is caused by daily wear and tear of the joint.
[1] [2] Specifically, arthralgia is a symptom of injury, infection, illness (in particular arthritis), or an allergic reaction to medication. [ 3 ] According to MeSH , the term arthralgia should only be used when the condition is non-inflammatory, and the term arthritis should be used when the condition is inflammatory .
While there are over 100 types of arthritis and related conditions, Dr. Gendai Echezona, a fellowship-trained, triple board-certified anesthesiologist specializing in interventional pain ...
Pain can often be severe, especially if teeth and/or a branch of the trigeminal nerve is involved, but many patients do not experience pain, at least in the earlier stages. When severe facial pain is purported to be caused by osteonecrosis, the term NICO, for neuralgia-inducing cavitational osteonecrosis , is sometimes used, but this is ...
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